Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | PPARD | Q03181 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL339492 | 0.87 | ALOX15 (0.81) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL8373906 | 0.86 | ALOX15 (0.61) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL9832704 | 0.83 | ALOX15 (0.63) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL166364 | 0.83 | ALOX15 (0.63) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL1249954 | 0.82 | ALOX15 (0.61) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL10399496 | 0.82 | ALOX15 (0.61) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL2336059 | 0.82 | ALOX15 (0.61) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL4781395 | 0.82 | ALOX15 (0.61) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL3854415 | 0.82 | ALOX15 (0.61) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 | |
| SCHEMBL18935767 | 0.81 | ALOX15 (0.65) | ALOX15ALDH1A1SMN1; SMN2FFAR1PTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406620-B1 | VINYL PHENYL DERIVATIVES AS GLK ACTIVATORS | ASTRAZENECA AB (SE) | 2006-11-02 | — | — | EP | disclosed |