Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725329 | 1.00 | OPRD1 (0.50) | OPRD1KMT2ADAGLBPTGESCYP1A2 | |
| SCHEMBL4834222 | 0.88 | CYP1A2 (0.40) | OPRD1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4794880 | 0.87 | OPRD1 (0.53) | OPRD1KMT2ADAGLBPTGESCYP1A2 | |
| SCHEMBL4781848 | 0.87 | OPRD1 (0.53) | OPRD1KMT2ADAGLBPTGESCYP1A2 | |
| SCHEMBL4725326 | 0.86 | OPRD1 (0.38) | OPRD1KMT2ADAGLBPTGESGHSR | |
| SCHEMBL1795969 | 0.80 | LMNA (0.43) | OPRD1 | |
| SCHEMBL1795967 | 0.80 | LMNA (0.43) | OPRD1 | |
| SCHEMBL8222689 | 0.80 | CHRNB4 (0.48) | CYP1A2CYP3A4CYP2C9CYP2C19GHSR | |
| SCHEMBL4778904 | 0.79 | OPRD1 (0.46) | OPRD1KMT2ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8220552 | 0.79 | OPRD1 (0.46) | OPRD1KMT2ACYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |