Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARK7 | Q99497 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 5/20 | 0.46 |
| ▸ | ALDH2 | P05091 | 4/20 | 0.46 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4785634 | 0.90 | PARK7 (0.61) | PARK7NPC1RAB9AALDH1A1GSK3B | |
| SCHEMBL4784997 | 0.86 | PARK7 (0.57) | PARK7NPC1RAB9AALDH1A1HTT | |
| SCHEMBL4783761 | 0.86 | GSK3B (0.59) | PARK7NPC1ALDH1A1GSK3BALDH3A1 | |
| SCHEMBL4784918 | 0.80 | PARK7 (0.67) | PARK7NPC1RAB9AALDH1A1GSK3B | |
| SCHEMBL9179332 | 0.74 | ALDH1A1 (0.62) | PARK7ALDH1A1GSK3BALDH3A1ALDH2 | |
| SCHEMBL4784991 | 0.74 | PARK7 (0.81) | PARK7ALDH1A1ALDH3A1ALDH2MAPT | |
| SCHEMBL22410739 | 0.74 | KMT2A (0.59) | PARK7NPC1RAB9AALDH1A1ALDH3A1 | |
| SCHEMBL18954539 | 0.71 | ALDH1A1 (0.62) | PARK7NPC1RAB9AALDH1A1ALDH3A1 | |
| SCHEMBL18954738 | 0.71 | PARK7 (0.50) | PARK7ALDH1A1ALDH3A1ALDH2CUL4A | |
| SCHEMBL4736331 | 0.70 | PARK7 (0.75) | PARK7ALDH1A1ALDH3A1ALDH2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008074078-A1 | SELECTIVELY DELIVERABLE ISATIN-BASED CYTOTOXIC AGENTS | UNIVERSITY OF WOLLONGONG (AU) | 2008-06-26 | — | — | WO | disclosed |