Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARK7 | Q99497 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | ALDH2 | P05091 | 4/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 4/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783761 | 0.88 | GSK3B (0.59) | PARK7NPC1GSK3BALDH1A1ALDH2 | |
| SCHEMBL4784997 | 0.88 | PARK7 (0.57) | PARK7NPC1RAB9AALDH1A1 | |
| SCHEMBL4785634 | 0.84 | PARK7 (0.61) | PARK7NPC1GSK3BRAB9AALDH1A1 | |
| SCHEMBL4735921 | 0.81 | PARK7 (1.00) | PARK7GSK3BALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL4781965 | 0.80 | PARK7 (0.52) | PARK7NPC1GSK3BRAB9AALDH1A1 | |
| SCHEMBL4786048 | 0.79 | PARK7 (0.78) | PARK7GSK3BALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL4781976 | 0.74 | PARK7 (0.71) | PARK7ALDH1A1ALDH2ALDH3A1CHRM5 | |
| SCHEMBL1609155 | 0.74 | NPC1 (1.00) | NPC1GSK3BRAB9APAX8ALDH1A1 | |
| SCHEMBL9179332 | 0.74 | ALDH1A1 (0.62) | PARK7GSK3BALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL18954539 | 0.73 | ALDH1A1 (0.62) | PARK7NPC1RAB9AALDH1A1ALDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008074078-A1 | SELECTIVELY DELIVERABLE ISATIN-BASED CYTOTOXIC AGENTS | UNIVERSITY OF WOLLONGONG (AU) | 2008-06-26 | — | — | WO | disclosed |