Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARK7 | Q99497 | 3/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CDYL2 | Q8N8U2 | 4/20 | 0.49 |
| ▸ | CDYL | Q9Y232 | 4/20 | 0.49 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 4/20 | 0.49 |
| ▸ | CBX7 | O95931 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784918 | 0.88 | PARK7 (0.67) | PARK7ALDH1A1NPC1RAB9A | |
| SCHEMBL4781965 | 0.86 | PARK7 (0.52) | PARK7MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL4785634 | 0.84 | PARK7 (0.61) | PARK7CA12ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL4783761 | 0.80 | GSK3B (0.59) | PARK7MAPTALDH1A1NPC1CHRM1 | |
| SCHEMBL4737404 | 0.80 | PARK7 (0.76) | PARK7MAPTALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL4785342 | 0.79 | PARK7 (0.72) | PARK7ALDH1A1 | |
| SCHEMBL29236730 | 0.79 | NPC1 (0.72) | CA12CA9CA1CDYL2CDYL | |
| SCHEMBL4735921 | 0.73 | PARK7 (1.00) | PARK7CA12CA9CA1MAPT | |
| SCHEMBL9179332 | 0.72 | ALDH1A1 (0.62) | PARK7MAPTALDH1A1TP53HTT | |
| SCHEMBL4786048 | 0.71 | PARK7 (0.78) | PARK7CA12CA9CA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008074078-A1 | SELECTIVELY DELIVERABLE ISATIN-BASED CYTOTOXIC AGENTS | UNIVERSITY OF WOLLONGONG (AU) | 2008-06-26 | — | — | WO | disclosed |