SCHEMBL4782203

SCHEMBL4782203

O=Cc1c(Br)c(Br)cn1-c1ncccc1Cl

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 1/20 0.36
TRIM33 Q9UPN9 1/20 0.36
HSD11B1 P28845 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SLC22A12 Q96S37 1/20 0.32
MALT1 Q9UDY8 1/20 0.32
TRPA1 O75762 1/20 0.32
RPS6KA5 O75582 2/20 0.32
TRPV1 Q8NER1 1/20 0.31
NFE2L2 Q16236 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27727985 0.81 RPS6KA5 (0.37) TRIM24TRIM33HSD11B1HTTSMN1; SMN2
SCHEMBL4784077 0.81 HTT (0.35) TRIM24TRIM33HSD11B1HTTSMN1; SMN2
SCHEMBL27727896 0.76 RPS6KA5 (0.38) HSD11B1HTTSMN1; SMN2MALT1TRPA1
SCHEMBL950752 0.74 ALDH1A1 (0.36) TRIM24TRIM33HSD11B1HTTSMN1; SMN2
SCHEMBL950203 0.71 TRPA1 (0.36) HSD11B1HTTSMN1; SMN2MALT1TRPA1
SCHEMBL950454 0.70 ALDH1A1 (0.46) TRIM24TRIM33HSD11B1RPS6KA5
SCHEMBL950762 0.69 TRPV1 (0.33) HSD11B1HTTSMN1; SMN2MALT1TRPA1
SCHEMBL950253 0.69 TRIM24 (0.36) TRIM24TRIM33HSD11B1SLC22A12MALT1
SCHEMBL951389 0.69 TRIM24 (0.36) TRIM24TRIM33HSD11B1SLC22A12MALT1
SCHEMBL955150 0.68 TRIM24 (0.38) TRIM24TRIM33HSD11B1MALT1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1937664-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME Sumitomo Chemical Company, Limited (JP) 2008-07-02 EP disclosed
WO-2007043677-A9 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2007-06-07 WO disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 WO disclosed