SCHEMBL27727896

SCHEMBL27727896

O=Cc1c(Cl)ccn1-c1ncccc1Cl

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RPS6KA5 O75582 4/20 0.38
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
RPS6KA4 O75676 1/20 0.35
HSD11B1 P28845 1/20 0.35
MALT1 Q9UDY8 1/20 0.34
TRPA1 O75762 1/20 0.34
NFE2L2 Q16236 3/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TRPV1 Q8NER1 1/20 0.33
MET P08581 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27727985 0.86 RPS6KA5 (0.37) RPS6KA5HTTSMN1; SMN2RPS6KA4HSD11B1
SCHEMBL4784077 0.79 HTT (0.35) RPS6KA5HTTSMN1; SMN2HSD11B1MALT1
SCHEMBL950454 0.77 ALDH1A1 (0.46) RPS6KA5HSD11B1ALDH1A1
SCHEMBL27727907 0.77 PTK2 (0.42) HTTSMN1; SMN2ALDH1A1KMT2ATDP1
SCHEMBL4782203 0.76 TRIM24 (0.36) RPS6KA5HTTSMN1; SMN2HSD11B1MALT1
SCHEMBL27727881 0.73 MALT1 (0.41) RPS6KA5SMN1; SMN2MALT1TRPA1MEN1
SCHEMBL950203 0.72 TRPA1 (0.36) HTTSMN1; SMN2HSD11B1MALT1TRPA1
SCHEMBL8500406 0.70 RPS6KA5 (0.40) RPS6KA5RPS6KA4HSD11B1MALT1TRPA1
SCHEMBL950451 0.70 ALDH1A1 (0.36) HSD11B1MALT1TRPA1NFE2L2MEN1
SCHEMBL950762 0.70 TRPV1 (0.33) RPS6KA5HTTSMN1; SMN2HSD11B1MALT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101287721-B Hydrazide compound and pesticidal use of the same SUMITOMO CO LTD 2013-03-27 CN disclosed
CN-101287721-A Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL CO (JP) 2008-10-15 CN disclosed