Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.38 |
| ▸ | EPHA3 | P29320 | 1/20 | 0.38 |
| ▸ | FRK | P42685 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 7/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.35 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.34 |
| ▸ | DDT | P30046 | 2/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778561 | 0.85 | DDT (0.45) | DDT | |
| SCHEMBL4779210 | 0.84 | TEK (0.41) | DDT | |
| SCHEMBL4784000 | 0.83 | DDT (0.34) | DDT | |
| SCHEMBL4780132 | 0.81 | RAF1 (0.40) | — | |
| SCHEMBL4782092 | 0.81 | BRAF (0.34) | DDTHTR1A | |
| SCHEMBL4730805 | 0.81 | DDT (0.42) | MAPK14DDT | |
| SCHEMBL4781066 | 0.79 | MAPK14 (0.55) | MAPK14EPHA3FRK | |
| SCHEMBL4782901 | 0.79 | BRAF (0.45) | DDT | |
| SCHEMBL4782957 | 0.78 | BRAF (0.42) | GLS | |
| SCHEMBL4783784 | 0.78 | TEK (0.40) | DDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |