Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 18/20 | 0.35 |
| ▸ | RAF1 | P04049 | 16/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780817 | 0.92 | NR1I2 (0.36) | NR1I2 | |
| SCHEMBL4782033 | 0.84 | NR1I2 (0.35) | NR1I2 | |
| SCHEMBL4779207 | 0.83 | NR1I2 (0.38) | NR1I2 | |
| SCHEMBL4782863 | 0.83 | NR1I2 (0.40) | MAPK14NR1I2BRAFRAF1 | |
| SCHEMBL4779570 | 0.82 | SSTR4 (0.40) | NR1I2BRAF | |
| SCHEMBL4781607 | 0.82 | ACKR3 (0.41) | NR1I2 | |
| SCHEMBL4782188 | 0.81 | MEN1 (0.42) | MAPK14NR1I2 | |
| SCHEMBL4780707 | 0.81 | NR1I2 (0.36) | NR1I2 | |
| SCHEMBL4780027 | 0.81 | NR1I2 (0.36) | NR1I2 | |
| SCHEMBL4783774 | 0.81 | NR1I2 (0.36) | NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |