SCHEMBL4782882 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	KMT2A	Q03164	2/20	0.43

▸	SFRP1	Q8N474	3/20	0.40

▸	MEN1	O00255	1/20	0.40

▸	HTR6	P50406	2/20	0.39

▸	TSHR	P16473	1/20	0.39

▸	SMN1; SMN2	Q16637	1/20	0.39

▸	WNT3	P56703	1/20	0.38

▸	POLB	P06746	2/20	0.36

▸	RAB9A	P51151	1/20	0.36

▸	IKBKB	O14920	1/20	0.36

▸	ALDH1A1	P00352	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4784754	0.84	MAPT (0.48)	KMT2AMEN1HTR6TSHRSMN1; SMN2
SCHEMBL4782529	0.84	SFRP1 (0.56)	SFRP1HTR6WNT3
SCHEMBL4780921	0.84	SFRP1 (0.48)	SFRP1HTR6WNT3
Hydrochloric Acid SCHEMBL4781661	0.83	SFRP1 (0.55)	SFRP1HTR6WNT3
SCHEMBL4784394	0.82	HTR6 (0.50)	SFRP1HTR6WNT3
SCHEMBL4784256	0.82	SFRP1 (0.46)	SFRP1HTR6WNT3
SCHEMBL4781473	0.82	SFRP1 (0.46)	SFRP1HTR6WNT3
SCHEMBL4783391	0.82	SFRP1 (0.46)	SFRP1HTR6WNT3
SCHEMBL4783287	0.82	HTR6 (0.47)	SFRP1HTR6WNT3
SCHEMBL4783281	0.82	HTR6 (0.47)	SFRP1HTR6WNT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2008060998-A1	INDOLE SULFONAMIDES AS SFRP-1 MODULATORS	WYETH (US)	2008-05-22	—	—	WO	disclosed