Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781558 | 0.84 | GLS (0.41) | ACKR3RAB9AALDH1A1HPGD | |
| SCHEMBL4779207 | 0.83 | NR1I2 (0.38) | ACKR3USP30 | |
| SCHEMBL4782188 | 0.83 | MEN1 (0.42) | ACKR3DRD2ALDH1A1 | |
| SCHEMBL4781607 | 0.82 | ACKR3 (0.41) | ACKR3RAB9A | |
| SCHEMBL4783774 | 0.81 | NR1I2 (0.36) | USP30 | |
| SCHEMBL4780817 | 0.81 | NR1I2 (0.36) | USP30 | |
| SCHEMBL4780027 | 0.81 | NR1I2 (0.36) | ACKR3USP30 | |
| SCHEMBL4779570 | 0.80 | SSTR4 (0.40) | ACKR3 | |
| SCHEMBL4782033 | 0.80 | NR1I2 (0.35) | USP30 | |
| SCHEMBL4780707 | 0.80 | NR1I2 (0.36) | ACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |