Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 10/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | TEK | Q02763 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779207 | 0.93 | NR1I2 (0.38) | NR1I2CNR2IRAK4KLKB1USP30 | |
| SCHEMBL4783784 | 0.90 | TEK (0.40) | NR1I2CNR1CNR2TEK | |
| SCHEMBL4780027 | 0.87 | NR1I2 (0.36) | NR1I2IRAK4KLKB1USP30TEK | |
| SCHEMBL4782188 | 0.84 | MEN1 (0.42) | NR1I2 | |
| SCHEMBL4782621 | 0.84 | GLS (0.43) | NR1I2KLKB1 | |
| SCHEMBL4782886 | 0.83 | NR1I2 (0.38) | NR1I2IRAK4GPR119 | |
| SCHEMBL4799754 | 0.83 | MAPK14 (0.37) | NR1I2CNR1TYK2PDE4DCNR2 | |
| SCHEMBL4783414 | 0.83 | NR1I2 (0.35) | NR1I2CNR2IRAK4USP30GPR119 | |
| SCHEMBL4782660 | 0.83 | NR1I2 (0.42) | NR1I2KLKB1USP30TEK | |
| SCHEMBL4779210 | 0.82 | TEK (0.41) | NR1I2TEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |