Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 16/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4782095 | 0.87 | HTR6 (0.48) | HTR6LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4797587 | 0.83 | AKR1C3 (0.48) | HTR6LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4784125 | 0.83 | HTR6 (0.48) | HTR6LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4782718 | 0.81 | HTR6 (0.49) | HTR6LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4781315 | 0.80 | HTR6 (0.45) | HTR6LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4783123 | 0.80 | HTR6 (0.45) | HTR6LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4785309 | 0.80 | HTR6 (0.43) | HTR6LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL14207893 | 0.78 | HTR6 (0.60) | HTR6LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4785858 | 0.77 | MEN1 (0.62) | HTR6LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4783073 | 0.77 | HTR6 (0.45) | HTR6LMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008060998-A1 | INDOLE SULFONAMIDES AS SFRP-1 MODULATORS | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |
| WO-2008060998-A1 | INDOLE SULFONAMIDES AS SFRP-1 MODULATORS | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |