Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781323 | 0.87 | HTR6 (0.43) | HTR6LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4782672 | 0.81 | ALDH1A1 (0.37) | HTR6LMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL4783408 | 0.80 | HTR6 (0.47) | HTR6LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4784125 | 0.80 | HTR6 (0.48) | HTR6LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4797587 | 0.80 | AKR1C3 (0.48) | HTR6LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4785006 | 0.79 | HTR6 (0.43) | HTR6MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4783391 | 0.79 | SFRP1 (0.46) | HTR6 | |
| SCHEMBL4783395 | 0.79 | SFRP1 (0.46) | HTR6 | |
| SCHEMBL4782718 | 0.78 | HTR6 (0.49) | HTR6LMNASMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4781665 | 0.78 | HTR6 (0.42) | HTR6MEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008060998-A1 | INDOLE SULFONAMIDES AS SFRP-1 MODULATORS | WYETH (US) | 2008-05-22 | — | — | WO | disclosed |