Saccharin

Saccharin

SCHEMBL4783567

C=CCNC(C)(C)c1ccccc1.O=C1NS(=O)(=O)c2ccccc21

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.52
CA2 P00918 5/20 0.52
CA9 Q16790 5/20 0.52
CA1 P00915 2/20 0.52
KDM4E B2RXH2 1/20 0.52
USP2 O75604 1/20 0.52
LMNA P02545 1/20 0.52
BCHE P06276 1/20 0.52
CA4 P22748 1/20 0.52
CA6 P23280 1/20 0.52
CA5A P35218 1/20 0.52
CA7 P43166 1/20 0.52
KMT2A Q03164 1/20 0.52
CA14 Q9ULX7 1/20 0.52
CA5B Q9Y2D0 1/20 0.52
ALDH1A1 P00352 2/20 0.41
ALPL P05186 2/20 0.38
ALPI P09923 2/20 0.38
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL130070 0.77 KCNN4 (0.41) KDM4EKMT2AALDH1A1GAATSHR
Acetic Acid SCHEMBL5720116 0.76 ALDH1A1 (0.45) KDM4ELMNAKMT2AALDH1A1GAA
Saccharin SCHEMBL27898163 0.76 CA12 (0.79) CA12CA2CA9CA1KDM4E
Hydrochloric Acid SCHEMBL173850 0.76 ATM (0.42) KDM4EKMT2AALDH1A1GAATSHR
Bromide SCHEMBL1261498 0.76 ALDH1A1 (0.40) KDM4EKMT2AALDH1A1GAATSHR
Saccharin SCHEMBL28495478 0.75 CA12 (0.67) CA12CA2CA9CA1KDM4E
Saccharin SCHEMBL28389154 0.75 CA12 (0.71) CA12CA2CA9CA1KDM4E
Saccharin SCHEMBL8770860 0.75 CA12 (0.71) CA12CA2CA9CA1KDM4E
Saccharin SCHEMBL9593061 0.74 CA12 (0.96) CA12CA2CA9CA1KDM4E
Succinic Acid SCHEMBL7270162 0.74 ALDH1A1 (0.43) KDM4ELMNAKMT2AALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080182125-A1 Cationic latex as a carrier for bioactive ingredients and its use in wallboard manufacture MICROBAN PRODUCTS COMPANY (US) 2008-07-31 US disclosed
WO-2008024470-A2 CATIONIC LATEX AS A CARRIER FOR BIOACTIVE INGREDIENTS AND ITS USE IN WALLBOARD MANUFACTURE MICROBAN PRODUCTS COMPANY (US) 2008-02-28 WO disclosed