Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.39 |
| ▸ | DPP4 known ✓ | P27487 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL130070 | 0.98 | KCNN4 (0.41) | ATMALDH1A1SMN1; SMN2KDM4EKCNN4 | |
| Bromide SCHEMBL1261498 | 0.96 | ALDH1A1 (0.40) | ATMALDH1A1SMN1; SMN2KDM4EKCNN4 | |
| Acetic Acid SCHEMBL5720116 | 0.90 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2KDM4EGAAMAPK1 | |
| SCHEMBL9567759 | 0.88 | HTT (0.41) | ALDH1A1SMN1; SMN2KDM4EGAATSHR | |
| Succinic Acid SCHEMBL7270162 | 0.87 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2KDM4EGAAMAPK1 | |
| Succinic Acid SCHEMBL7270158 | 0.87 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2KDM4EGAAMAPK1 | |
| SCHEMBL7735572 | 0.85 | GAA (0.36) | ATMALDH1A1SMN1; SMN2KDM4EKCNN4 | |
| SCHEMBL8776711 | 0.80 | ALDH1A1 (0.51) | ATMALDH1A1SMN1; SMN2KDM4EKCNN4 | |
| Ditiocarb SCHEMBL10336216 | 0.80 | GAA (0.40) | ALDH1A1SMN1; SMN2KDM4EGAAMAPK1 | |
| SCHEMBL10336217 | 0.79 | GAA (0.39) | ALDH1A1SMN1; SMN2KDM4EGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1075 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118339269-A | Laundry sanitizing and softening compositions | 雷克特本克斯尔健康有限公司 | 2024-07-12 | — | — | CN | claimed |
| US-20240215791-A1 | SURFACE WIPING APPARATUS | STANTON SUZANNE (US) | 2024-07-04 | — | — | US | claimed |
| US-20240216298-A1 | TOPICAL TREATMENT OF HERPES INFECTIONS | TECH SWERVE, LLC | 2024-07-04 | — | — | US | claimed |
| CN-118234379-A | Preservative composition | 阿尔萨达股份公司 | 2024-06-21 | — | — | CN | claimed |
| US-20240026312-A1 | PURIFICATION OF PROTEINS WITH CATIONIC SURFACTANT | HORIZON THERAPEUTICS USA, INC. | 2024-01-25 | — | — | US | claimed |
| CN-117355629-A | Method and system for coating filter media | 分子等离子集团股份有限公司 | 2024-01-05 | — | — | CN | claimed |
| CN-114557346-B | Mildew-removal anti-blocking composition, application thereof and mildew-removal anti-blocking sheet | 浙江康星科技有限公司 | 2024-01-05 | — | — | CN | claimed |
| CN-116806139-A | Dual phase composition for cleansing and/or removing makeup from keratin materials | 莱雅公司 | 2023-09-26 | — | — | CN | claimed |
| CN-116478678-A | Fracturing acidification high-temperature corrosion inhibitor composition and preparation method thereof | 成都顺达利聚合物有限公司 | 2023-07-25 | — | — | CN | claimed |
| CN-116438285-A | Aqueous cleaning composition comprising nonionic surfactant, quaternary ammonium compound and chelating agent | 联合利华知识产权控股有限公司 | 2023-07-14 | — | — | CN | claimed |
| EP-0505023-A1 | Synergistic, additive or antagonistic product selection test for biocides | NALCO CHEMICAL COMPANY (US) | 1992-09-23 | — | — | EP | claimed |
| US-5034207-A | Agitation water, sodium silicate and sulfuric acid, filtration, washing a filter cake | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1991-07-23 | — | — | US | claimed |
| US-4786696-A | EMULSION POLYMERIZATION OF ACRYLATE MONOMERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-11-22 | — | — | US | claimed |
| US-4783340-A | QUATERNARY AMMONIUM COMPOUND, ACID POLYMER | ECOLAB INC. (US) | 1988-11-08 | — | — | US | claimed |
| US-4552692-A | Concentrated composition for cleaning rugs and carpets | GILLESPIE THOMAS W | 1985-11-12 | — | — | US | claimed |
| US-4472283-A | QUATERNARY AMMONIUM COMPOUNDS TO SLOW LOSS OF CARBON DIOXIDE | CITICORP. USA, INC. | 1984-09-18 | — | — | US | claimed |
| US-4460487-A | HYDROGEN PEROXIDE, CATIONIC AMINE SOFTENER | PUREX CORPORATION (US) | 1984-07-17 | — | — | US | claimed |
| US-4311512-A | Bactericidal water-soluble complexes | POLYCRAFT LABORATORIES, INC., A CORP. OF NJ. | 1982-01-19 | — | — | US | claimed |
| US-4083832-A | Blood compatible vessels and components thereof | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1978-04-11 | — | — | US | claimed |
| US-4069066-A | AMINE COMPOUNDS, METAL SALT | THE PROCTER & GAMBLE COMPANY (US) | 1978-01-17 | — | — | US | claimed |