Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL130070 | 0.91 | KCNN4 (0.41) | ALDH1A1SMN1; SMN2KDM4ETSHRGAA | |
| Succinic Acid SCHEMBL7270158 | 0.90 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2KDM4ETSHRGAA | |
| Succinic Acid SCHEMBL7270162 | 0.90 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2KDM4ETSHRGAA | |
| Bromide SCHEMBL1261498 | 0.90 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2KDM4ETSHRGAA | |
| Hydrochloric Acid SCHEMBL173850 | 0.90 | ATM (0.42) | ALDH1A1SMN1; SMN2KDM4ETSHRGAA | |
| SCHEMBL9567759 | 0.85 | HTT (0.41) | ALDH1A1SMN1; SMN2KDM4ETSHRGAA | |
| SCHEMBL7735572 | 0.79 | GAA (0.36) | ALDH1A1SMN1; SMN2KDM4EGAAMAPK1 | |
| Ditiocarb SCHEMBL10336216 | 0.77 | GAA (0.40) | ALDH1A1SMN1; SMN2KDM4EGAAMAPK1 | |
| Saccharin SCHEMBL4783567 | 0.76 | CA12 (0.52) | ALDH1A1KDM4ETSHRGAAHTT | |
| SCHEMBL10336217 | 0.76 | GAA (0.39) | ALDH1A1SMN1; SMN2KDM4EGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464630-B1 | Aqueous coating liquid for forming a magnesium oxide film | NOF CORP (JP) | 2006-05-10 | — | — | EP | disclosed |
| US-6911072-B2 | Aqueous coating liquid for forming a magnesium oxide film | NOF CORPORATION (JP) | 2005-06-28 | — | — | US | disclosed |
| US-20040247505-A1 | Aqueous coating liquid for forming a magnesium oxide film | NOF CORPORATION (JP) | 2004-12-09 | — | — | US | disclosed |
| EP-1464630-A1 | Aqueous coating liquid for forming a magnesium oxide film | NOF CORPORATION (JP) | 2004-10-06 | — | — | EP | disclosed |