Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 2/20 | 0.35 |
| ▸ | XDH | P47989 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | ITK | Q08881 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4734620 | 0.89 | MKNK1 (0.43) | MKNK1MKNK2XDHCASP3SCN10A | |
| SCHEMBL22492769 | 0.81 | HTT (0.46) | HTTHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL5242504 | 0.81 | HTT (0.46) | HTTHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL28391899 | 0.77 | MKNK1 (0.46) | MKNK1MKNK2HTTHSD17B10KDM4E | |
| SCHEMBL4783818 | 0.74 | MAPT (0.38) | HTTHSD17B10KDM4EERN1MAPT | |
| SCHEMBL1582996 | 0.74 | ALDH1A1 (0.46) | HTTHSD17B10KDM4EMAPTTSHR | |
| SCHEMBL21326982 | 0.72 | LMNA (0.36) | MAPT | |
| SCHEMBL4735127 | 0.72 | MKNK1 (0.68) | MKNK1MKNK2XDHSCN10AAXL | |
| SCHEMBL14041696 | 0.71 | HTT (0.65) | MKNK1MKNK2HTTMAPTSMN1; SMN2 | |
| SCHEMBL4736049 | 0.71 | HTT (0.65) | MKNK1MKNK2HTTMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008070350-A9 | METHODS AND COMPOSITIONS RELATED TO WRAPPING OF DEHYDRONS | UNIV TEXAS (US) | 2008-10-23 | — | — | WO | disclosed |
| WO-2008070350-A2 | METHODS AND COMPOSITIONS RELATED TO WRAPPING OF DEHYDRONS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2008-06-12 | — | — | WO | disclosed |