Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 11/20 | 0.37 |
| ▸ | HTR3A | P46098 | 2/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783842 | 0.91 | TEK (0.38) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL4779570 | 0.86 | SSTR4 (0.40) | NR1I2GPR119 | |
| SCHEMBL4781607 | 0.86 | ACKR3 (0.41) | NR1I2GPR119 | |
| SCHEMBL4780707 | 0.85 | NR1I2 (0.36) | NR1I2GPR119 | |
| SCHEMBL4780817 | 0.82 | NR1I2 (0.36) | NR1I2USP30GPR119 | |
| SCHEMBL4782033 | 0.82 | NR1I2 (0.35) | NR1I2USP30GPR119 | |
| SCHEMBL4779207 | 0.81 | NR1I2 (0.38) | NR1I2USP30GPR119 | |
| SCHEMBL4783140 | 0.81 | MAPK14 (0.36) | NR1I2 | |
| SCHEMBL4782188 | 0.80 | MEN1 (0.42) | NR1I2 | |
| SCHEMBL4782925 | 0.79 | ACKR3 (0.51) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |