Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 16/20 | 0.46 |
| ▸ | MAOA | P21397 | 4/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7443073 | 1.00 | MAOB (0.46) | MAOBMAOAADORA2BNPC1MAPT | |
| SCHEMBL31722071 | 1.00 | MAOB (0.46) | MAOBMAOAADORA2BNPC1MAPT | |
| SCHEMBL5761877 | 0.79 | TSHR (0.50) | MAOBMAOAADORA2BNPC1MAPT | |
| Ammonia Solution, Strong SCHEMBL5763481 | 0.78 | TSHR (0.49) | MAOBMAOAADORA2BNPC1MAPT | |
| SCHEMBL5164924 | 0.77 | MAOB (0.54) | MAOBMAOAADORA2BNPC1MAPT | |
| SCHEMBL4474110 | 0.76 | MAOB (0.47) | MAOBMAOAADORA2BNPC1PSMB8 | |
| SCHEMBL13134182 | 0.75 | MAOB (0.45) | MAOBMAOAADORA2BNPC1MAPT | |
| SCHEMBL29093498 | 0.73 | MAOA (0.59) | MAOANPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL246709 | 0.73 | ALDH1A1 (0.57) | RAB9A | |
| SCHEMBL4600933 | 0.73 | ALDH1A1 (0.57) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008068621-A2 | COMBINATION PRODUCT WITH IDO INHIBITOR AND TUMOR TARGETED IFN-GAMMA | MOLMED SPA (IT) | 2008-06-12 | — | — | WO | disclosed |