Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 14/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781438 | 0.89 | ESR1 (0.37) | PIK3CAPIK3R1PIK3CBPIK3CGMTOR | |
| SCHEMBL4786674 | 0.84 | POLB (0.40) | KDRPIK3CAPIK3R1 | |
| SCHEMBL4784449 | 0.84 | PIK3CA (0.49) | PIK3CAPIK3CBPIK3CGMTORPIK3CD | |
| SCHEMBL4782724 | 0.83 | PIK3CA (0.57) | PIK3CAPIK3R1PIK3CBPIK3CGMTOR | |
| SCHEMBL4785206 | 0.83 | KDR (0.42) | KDRPIK3CAPIK3R1PIK3CBPIK3CG | |
| SCHEMBL4785750 | 0.80 | PIK3CA (0.36) | PIK3CAPIK3R1 | |
| SCHEMBL4784015 | 0.78 | HTR2A (0.44) | PIK3CAKDM4EMTOR | |
| SCHEMBL4783015 | 0.78 | PIK3CA (0.48) | PIK3CAPIK3R1PIK3CGMTOR | |
| SCHEMBL4785148 | 0.78 | ESR1 (0.42) | PIK3CAMTOR | |
| SCHEMBL4783923 | 0.77 | HRH4 (0.43) | PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | claimed |
| WO-2008072850-A1 | TRIAZINE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST ACETYL-COA CARBOXYLASE | AMOREPACIFIC CORPORATION (KR) | 2008-06-19 | — | — | WO | disclosed |