Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 10/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.35 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784650 | 0.85 | CTSA (0.34) | POLBADORA1ADORA2ACTSATGFBR1 | |
| SCHEMBL8267148 | 0.83 | HTT (0.36) | ADORA1ADORA2ACTSATGFBR1ADORA3 | |
| SCHEMBL8381196 | 0.80 | PDE4A (0.36) | POLBADORA1ADORA2ACTSAADORA3 | |
| SCHEMBL7922066 | 0.80 | RIPK1 (0.31) | CTSARIPK1RIPK3CYP1A2CYP3A4 | |
| SCHEMBL14104139 | 0.70 | RAB9A (0.50) | AXLMKNK1MKNK2POLBADORA1 | |
| SCHEMBL2408413 | 0.70 | TGFBR1 (0.60) | AXLMKNK1MKNK2POLBADORA1 | |
| SCHEMBL14103869 | 0.69 | RAB9A (0.47) | AXLMKNK1MKNK2POLBKDM4E | |
| SCHEMBL1367259 | 0.68 | AXL (0.52) | AXLMKNK1MKNK2POLBADORA1 | |
| SCHEMBL14842277 | 0.67 | AXL (0.37) | AXLMKNK1MKNK2POLBADORA1 | |
| SCHEMBL4744102 | 0.66 | PDE4A (0.56) | AXLMKNK1MKNK2ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008086053-A1 | HCV INHIBITORS | VIROBAY, INC. (US) | 2008-07-17 | — | — | WO | disclosed |
| WO-2008086053-A1 | HCV INHIBITORS | VIROBAY, INC. (US) | 2008-07-17 | — | — | WO | disclosed |
| US-20080161254-A1 | HCV INHIBITORS | VIROBAY, INC. (US) | 2008-07-03 | — | — | US | disclosed |
| US-20080161254-A1 | HCV INHIBITORS | VIROBAY, INC. (US) | 2008-07-03 | — | — | US | disclosed |
| US-20080161254-A1 | HCV INHIBITORS | VIROBAY, INC. (US) | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161254-A1 | HCV INHIBITORS | HAVCR2, ZC3HAV1, EIF2AK2 | AXL 4125/4885MKNK1 2359/4885MKNK2 2861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.