Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 3/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | MGLL | Q99685 | 4/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19387636 | 0.86 | TPSAB1 (0.52) | PARP14PARP10 | |
| SCHEMBL10720101 | 0.84 | PARP14 (0.65) | PARP14PARP10NAMPTNPC1MGLL | |
| SCHEMBL4785020 | 0.82 | PARP14 (0.60) | PARP14PARP10NAMPTNPC1MGLL | |
| SCHEMBL3379832 | 0.81 | PARP1 (0.53) | PARP14PARP10NAMPTNPC1CA12 | |
| SCHEMBL26315228 | 0.80 | L3MBTL3 (0.64) | PARP14PARP10NAMPTNPC1MGLL | |
| SCHEMBL4206605 | 0.80 | CA12 (0.71) | PARP14PARP10NAMPTNPC1CA12 | |
| SCHEMBL14368303 | 0.78 | SIGMAR1 (0.56) | — | |
| SCHEMBL27308613 | 0.78 | KMT2A (0.45) | MGLLLMNAKDM4EALDH1A1TSHR | |
| SCHEMBL14368302 | 0.78 | EPHX2 (0.57) | ALDH1A1TSHRTP53 | |
| SCHEMBL1197337 | 0.78 | PARP14 (0.59) | PARP14PARP10NAMPTNPC1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059214-A1 | BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-05-22 | — | — | WO | disclosed |