Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786703 | 0.84 | CYP3A4 (0.41) | ALDH1A1TDP1CYP2C19L3MBTL1KMT2A | |
| SCHEMBL28455412 | 0.80 | GPR84 (0.52) | TDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL8489074 | 0.75 | L3MBTL1 (0.44) | DPP7MMP1MMP2MMP8ALDH1A1 | |
| SCHEMBL8487636 | 0.73 | L3MBTL1 (0.42) | DPP7MMP1MMP2MMP8TDP1 | |
| SCHEMBL28910831 | 0.72 | KDM4E (0.39) | ALDH1A1TDP1CNR2KMT2AMEN1 | |
| SCHEMBL4440119 | 0.71 | KMT2A (0.62) | ALDH1A1TDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL3124110 | 0.71 | GPR84 (0.57) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL4560650 | 0.71 | MMP1 (0.44) | DPP7MMP1MMP2MMP8ALDH1A1 | |
| SCHEMBL18959431 | 0.70 | MMP1 (0.41) | DPP7MMP1MMP2MMP8LIPE | |
| SCHEMBL31686221 | 0.70 | MMP1 (0.41) | DPP7MMP1MMP2MMP8LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124582-A1 | RENIN INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-16 | — | — | WO | disclosed |