SCHEMBL4785589

SCHEMBL4785589

C=CC#Cc1ccc(-c2cccs2)s1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 4/20 0.44
LTA4H P09960 1/20 0.41
ALDH1A1 P00352 7/20 0.39
KDM4E B2RXH2 6/20 0.39
L3MBTL1 Q9Y468 4/20 0.39
GAA P10253 3/20 0.39
MAPT P10636 3/20 0.39
LMNA P02545 2/20 0.39
GLA P06280 2/20 0.39
MEN1 O00255 3/20 0.38
HPGD P15428 3/20 0.38
KMT2A Q03164 3/20 0.38
HSD17B10 Q99714 3/20 0.38
NPC1 O15118 3/20 0.38
RAB9A P51151 3/20 0.38
POLB P06746 2/20 0.38
CASP1 P29466 2/20 0.38
CASP7 P55210 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12964717 0.84 LTA4H (0.50) DPP4LTA4HALDH1A1KDM4EL3MBTL1
SCHEMBL12964715 0.82 DPP4 (0.52) DPP4LTA4HALDH1A1KDM4EL3MBTL1
SCHEMBL6852454 0.81 LTA4H (0.44) DPP4LTA4HALDH1A1KDM4EL3MBTL1
SCHEMBL499299 0.77 ALDH1A1 (0.46) DPP4LTA4HALDH1A1KDM4EL3MBTL1
SCHEMBL8013270 0.73 DPP4 (0.51) DPP4LTA4HALDH1A1KDM4EL3MBTL1
SCHEMBL13084161 0.73 LTA4H (0.41) DPP4LTA4HALDH1A1KDM4EL3MBTL1
SCHEMBL498548 0.73 LTA4H (0.47) DPP4LTA4HALDH1A1KDM4EL3MBTL1
SCHEMBL8577680 0.73 ALDH1A1 (0.47) DPP4LTA4HALDH1A1KDM4EL3MBTL1
SCHEMBL13139111 0.72 GRM5 (0.44) DPP4LTA4HALDH1A1KDM4EL3MBTL1
SCHEMBL2021520 0.72 DPP4 (0.42) DPP4LTA4HALDH1A1KDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114907514-A Multifunctional fiber and preparation method and application thereof 北京洁尔爽高科技有限公司 2022-08-16 CN disclosed
US-10683244-B2 Method for controlling plant parasitic nematodes YAMASHITA THOMAS T (US) 2020-06-16 US disclosed
US-20190023627-A1 Compositions for Controlling Plant Parasitic Nematodes and Methods for Using Same YAMASHITA THOMAS T (US) 2019-01-24 US disclosed
US-10106472-B2 Compositions for controlling plant parasitic nematodes and methods for using same YAMASHITA THOMAS T (US) 2018-10-23 US disclosed
US-20170226024-A1 Compositions for Controlling Plant Parasitic Nematodes and Methods for Using Same YAMASHITA THOMAS T (US) 2017-08-10 US disclosed
US-9661857-B2 Compositions for controlling plant parasitic nematodes YAMASHITA THOMAS T (US) 2017-05-30 US disclosed
US-20150125435-A1 Compositions for Controlling Plant Parasitic Nematodes and Methods for Using Same YAMASHITA THOMAS T (US) 2015-05-07 US disclosed
WO-2008077570-A1 TRANSFORMATION OF TAGETES USING THE SELDA SELECTION MARKER BASF PLANT SCIENCE GMBH (DE) 2008-07-03 WO disclosed
CN-1285348-C Breast enlarging composition and its preparing method ZHANG HUAPING (CN) 2006-11-22 CN disclosed
EP-1240342-B1 PRODUCTION OF TRANSGENIC PLANTS OF THE TAGETES SPECIES SUNGENE GMBH & CO KGAA (DE) 2006-10-11 EP disclosed
CN-1569092-A Breast enlarging composition and its preparing method ZHANG HUAPING (CN) 2005-01-26 CN disclosed
US-20030033638-A1 Production of transgenic plants of the tagetes species SUNGENE GMBH & CO. KGAA (DE) 2003-02-13 US disclosed
US-5753692-A PLANT EXTRACTS, IMMUNOSTIMULANTS TREATING IMMUNODEFICIENCY DISEASES INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1998-05-19 US disclosed
US-5747525-A ANTITUMOR AGENTS OF OLIGOMERS OF THIOPHENE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1998-05-05 US disclosed
US-5602170-A ADMINISTERING ANTIIFLAMMATORY AGENT INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1997-02-11 US disclosed
EP-0538310-B1 ETHYNYLBENZOTHIOPHENE PESTICIDES FMC CORP (US) 1995-09-13 EP disclosed
WO-1992000672-A1 ETHYNYLBENZOTHIOPHENE PESTICIDES FMC CORPORATION (US) 1992-01-23 WO disclosed
US-5073564-A Photoactivated insecticides FMC CORPORATION (US) 1991-12-17 US disclosed