SCHEMBL8577680

SCHEMBL8577680

C#Cc1ccc(-c2cccs2)s1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.47
L3MBTL1 Q9Y468 5/20 0.47
NPC1 O15118 4/20 0.47
RAB9A P51151 4/20 0.47
GAA P10253 3/20 0.47
HSD17B10 Q99714 3/20 0.47
MEN1 O00255 3/20 0.47
HPGD P15428 3/20 0.47
KMT2A Q03164 3/20 0.47
LMNA P02545 2/20 0.47
POLB P06746 2/20 0.47
CASP1 P29466 2/20 0.47
CASP7 P55210 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
TP53 P04637 1/20 0.47
NFKB1 P19838 1/20 0.47
MAPK1 P28482 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47
LTA4H P09960 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22733855 0.98 DPP4 (0.49) ALDH1A1L3MBTL1NPC1RAB9AGAA
SCHEMBL12964717 0.83 LTA4H (0.50) ALDH1A1L3MBTL1NPC1RAB9AGAA
SCHEMBL1478213 0.82 HDAC8 (0.45) DPP4HDAC8
SCHEMBL12964715 0.82 DPP4 (0.52) ALDH1A1L3MBTL1NPC1RAB9AGAA
SCHEMBL14154229 0.80 HDAC8 (0.43) DPP4HDAC8
SCHEMBL498548 0.80 LTA4H (0.47) ALDH1A1L3MBTL1NPC1RAB9AGAA
SCHEMBL22763313 0.78 DPP4 (0.49) ALDH1A1L3MBTL1NPC1RAB9AGAA
SCHEMBL498818 0.78 DPP4 (0.49) ALDH1A1L3MBTL1NPC1RAB9AGAA
SCHEMBL18470974 0.78 ALDH1A1 (0.33) ALDH1A1L3MBTL1NPC1RAB9AGAA
SCHEMBL23611278 0.78 DPP4 (0.65) ALDH1A1L3MBTL1NPC1RAB9AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11352379-B2 Cyclic germanium compounds and applications thereof THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2022-06-07 US disclosed
US-20190225632-A1 CYCLIC GERMANIUM COMPOUNDS AND APPLICATIONS THEREOF THE CURATORS OF THE UNIVERSITY OF MISSOURI 2019-07-25 US disclosed
US-10294252-B2 Cyclic germanium compounds and applications thereof THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 2019-05-21 US disclosed
CN-103635482-B Purposes in cobalt complex active layer in preparing photovoltaic cell and corresponding photovoltaic cell 国立科学研究中心 2016-11-09 CN disclosed
US-9263683-B2 Use of cobalt complexes for preparing an active layer in a photovoltaic cell, and corresponding photovoltaic cell CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2016-02-16 US disclosed
EP-2691404-B1 USE OF COBALT COMPLEXES FOR THE PREPARATION OF THE ACTIVE LAYER OF A PHOTVOLTAIC CELL, AND CORRESPONDING PHOTOVOLTAIC CELL CENTRE NAT RECH SCIENT (FR) 2015-05-06 EP disclosed
US-20140290745-A1 USE OF COBALT COMPLEXES FOR PREPARING AN ACTIVE LAYER IN A PHOTOVOLTAIC CELL, AND CORRESPONDING PHOTOVOLTAIC CELL UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) 2014-10-02 US disclosed
US-20140290745-A1 USE OF COBALT COMPLEXES FOR PREPARING AN ACTIVE LAYER IN A PHOTOVOLTAIC CELL, AND CORRESPONDING PHOTOVOLTAIC CELL UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) 2014-10-02 US disclosed
US-20140290745-A1 USE OF COBALT COMPLEXES FOR PREPARING AN ACTIVE LAYER IN A PHOTOVOLTAIC CELL, AND CORRESPONDING PHOTOVOLTAIC CELL UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) 2014-10-02 US disclosed
CN-103635482-A Use of cobalt complexes for preparing an active layer in a photovoltaic cell, and corresponding photovoltaic cell CENTRE NAT RECH SCIENT 2014-03-12 CN disclosed
EP-2691404-A1 USE OF COBALT COMPLEXES FOR PREPARING AN ACTIVE LAYER IN A PHOTOVOLTAIC CELL, AND CORRESPONDING PHOTOVOLTAIC CELL Centre National De La Recherche Scientifique (FR) 2014-02-05 EP disclosed
US-20120264649-A1 AGENTS FOR ENHANCED CHARGE TRANSPORT ACROSS MICROBIAL MEMBRANES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2012-10-18 US disclosed
US-20120264649-A1 AGENTS FOR ENHANCED CHARGE TRANSPORT ACROSS MICROBIAL MEMBRANES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2012-10-18 US disclosed
WO-2012131257-A1 USE OF COBALT COMPLEXES FOR PREPARING AN ACTIVE LAYER IN A PHOTOVOLTAIC CELL, AND CORRESPONDING PHOTOVOLTAIC CELL CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2012-10-04 WO disclosed
WO-2012131257-A1 USE OF COBALT COMPLEXES FOR PREPARING AN ACTIVE LAYER IN A PHOTOVOLTAIC CELL, AND CORRESPONDING PHOTOVOLTAIC CELL CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2012-10-04 WO disclosed
US-5753692-A PLANT EXTRACTS, IMMUNOSTIMULANTS TREATING IMMUNODEFICIENCY DISEASES INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1998-05-19 US disclosed
US-5747525-A ANTITUMOR AGENTS OF OLIGOMERS OF THIOPHENE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1998-05-05 US disclosed
US-5602170-A ADMINISTERING ANTIIFLAMMATORY AGENT INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1997-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190225632-A1 CYCLIC GERMANIUM COMPOUNDS AND APPLICATIONS THEREOF GMNN, DCX, TRPA1 ALDH1A1 2241/4885L3MBTL1 2062/4885NPC1 3704/4885
US-11352379-B2 Cyclic germanium compounds and applications thereof GMNN, DCX, TRPA1 ALDH1A1 2241/4885L3MBTL1 2062/4885NPC1 3704/4885
US-10294252-B2 Cyclic germanium compounds and applications thereof GMNN, DCX, TRPA1 ALDH1A1 2258/4885L3MBTL1 2160/4885NPC1 3625/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.