SCHEMBL498548

SCHEMBL498548

N#Cc1ccc(-c2cccs2)s1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.47
DPP4 P27487 4/20 0.46
ALDH1A1 P00352 4/20 0.44
KDM4E B2RXH2 4/20 0.44
GAA P10253 3/20 0.44
L3MBTL1 Q9Y468 3/20 0.44
MAPT P10636 3/20 0.44
LMNA P02545 2/20 0.44
GLA P06280 2/20 0.44
POLB P06746 3/20 0.43
HSD17B10 Q99714 3/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
MEN1 O00255 2/20 0.43
HPGD P15428 2/20 0.43
CASP1 P29466 2/20 0.43
CASP7 P55210 2/20 0.43
KMT2A Q03164 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
TP53 P04637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22763313 0.98 DPP4 (0.49) LTA4HDPP4ALDH1A1KDM4EGAA
SCHEMBL498818 0.98 DPP4 (0.49) LTA4HDPP4ALDH1A1KDM4EGAA
SCHEMBL12964717 0.83 LTA4H (0.50) LTA4HDPP4ALDH1A1KDM4EGAA
SCHEMBL13074418 0.82 PGR (0.43) DPP4MAPK1
SCHEMBL12964715 0.82 DPP4 (0.52) LTA4HDPP4ALDH1A1KDM4EGAA
SCHEMBL498595 0.80 PGR (0.42) DPP4MAPK1
SCHEMBL8577680 0.80 ALDH1A1 (0.47) LTA4HDPP4ALDH1A1KDM4EGAA
SCHEMBL22733855 0.78 DPP4 (0.49) LTA4HDPP4ALDH1A1KDM4EGAA
SCHEMBL23611278 0.78 DPP4 (0.65) LTA4HDPP4ALDH1A1KDM4EGAA
Alpha-Terthienyl SCHEMBL147274 0.78 DPP4 (0.65) LTA4HDPP4ALDH1A1KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200388881-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH FUNCTIONAL THIOPHENE COMPOUNDS OR DERIVATIVES OF THIOPHENE CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION 2020-12-10 US claimed
WO-2024230718-A1 MICROENVIRONMENT VISCOSITY SENSITIVE FLUORESCENT DYE, PREPARATION METHOD THEREFOR, AND USE THEREOF 上海交通大学 2024-11-14 WO disclosed
CN-118930573-A Fluorescent dye sensitive to micro-environment viscosity and preparation method and application thereof 上海交通大学 2024-11-12 CN disclosed
US-11569530-B2 Silicon-based energy storage devices with functional thiophene compounds or derivatives of thiophene containing electrolyte additives ENEVATE CORPORATION (US) 2023-01-31 US disclosed
US-11569530-B2 Silicon-based energy storage devices with functional thiophene compounds or derivatives of thiophene containing electrolyte additives ENEVATE CORPORATION (US) 2023-01-31 US disclosed
US-20200388881-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH FUNCTIONAL THIOPHENE COMPOUNDS OR DERIVATIVES OF THIOPHENE CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION 2020-12-10 US disclosed
US-20200388881-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH FUNCTIONAL THIOPHENE COMPOUNDS OR DERIVATIVES OF THIOPHENE CONTAINING ELECTROLYTE ADDITIVES ENEVATE CORPORATION 2020-12-10 US disclosed
EP-2379109-B1 COMBINATION OF PHOTODYNAMIC THERAPY AND ANTI-VEGF AGENTS IN THE TREATMENT OF UNWANTED CHOROIDAL NEOVASCULATURE BAUSCH HEALTH COMPANIES INC (CA) 2020-10-07 EP disclosed
US-10431745-B2 Diketopyrrolopyrrole polymers for use in organic field effect transistors BASF SE (DE) 2019-10-01 US disclosed
EP-3456756-A2 DIKETOPYRROLOPYRROLE POLYMERS FOR USE IN ORGANIC FIELD EFFECT TRANSISTORS BASF SE (DE) 2019-03-20 EP disclosed
EP-1229937-A2 USE OF PDT TO INHIBIT INTIMAL HYPERPLASIA QLT Inc. (CA) 2002-08-14 EP disclosed
US-20020061330-A1 Supports for photosensitizer formulations BRITISH COLUMBIA, THE UNIVERSITY OF (CA) 2002-05-23 US disclosed
US-20020022032-A1 Immuno-adjuvant PDT treatment of metastatic tumors QLT INC. (CA) 2002-02-21 US disclosed
WO-2001085213-A2 SUPPORTS FOR PHOTOSENSITIZER FORMULATIONS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2001-11-15 WO disclosed
WO-2001085212-A2 DRUG DELIVERY SYSTEMS FOR PHOTODYNAMIC THERAPY THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2001-11-15 WO disclosed
WO-2001035996-A2 USE OF PDT TO INHIBIT INTIMAL HYPERPLASIA QLT INC. (CA) 2001-05-25 WO disclosed
WO-2001035997-A2 USE OF LOW-DOSE PDT TO INHIBIT RESTENOSIS QLT INC. (CA) 2001-05-25 WO disclosed
EP-0353667-B1 Bithienyl derivatives, process for their preparation, and compositions containing them BASF AG (DE) 1994-03-16 EP disclosed
US-5158598-A Insecticides, miticides, and nematocides; nonphytotoxic BASF AKTIENGESELLSCHAFT (DE) 1992-10-27 US disclosed
EP-0353667-A1 Bithienyl derivatives, process for their preparation, and compositions containing them BASF Aktiengesellschaft (DE) 1990-02-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020061330-A1 Supports for photosensitizer formulations PPOX, PPIF, SDHA LTA4H 1099/4885DPP4 2865/4885ALDH1A1 371/4885
US-11569530-B2 Silicon-based energy storage devices with functional thiophene compounds or derivatives of thiophene containing electrolyte additives TST, SELENOI, SELE LTA4H 2911/4885DPP4 2554/4885ALDH1A1 946/4885
US-20020022032-A1 Immuno-adjuvant PDT treatment of metastatic tumors CD74, ANXA11, ANXA1 LTA4H 846/4885DPP4 1489/4885ALDH1A1 794/4885
US-20200388881-A1 SILICON-BASED ENERGY STORAGE DEVICES WITH FUNCTIONAL THIOPHENE COMPOUNDS OR DERIVATIVES OF THIOPHENE CONTAINING ELECTROLYTE ADDITIVES TST, SELENOI, SELE LTA4H 2911/4885DPP4 2554/4885ALDH1A1 946/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.