Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 9/20 | 0.41 |
| ▸ | PLK1 | P53350 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.39 |
| ▸ | PRSS12 | P56730 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786016 | 0.91 | PTGES (0.44) | PTGESPLK1HDAC3HDAC1HDAC2 | |
| SCHEMBL4787275 | 0.91 | PTGES (0.41) | PTGESPRSS12SMN1; SMN2CYP2D6CYP2C9 | |
| SCHEMBL4786434 | 0.88 | PTGES (0.44) | PTGESPRSS12NPC1CYP2D6CYP2C9 | |
| SCHEMBL4785781 | 0.87 | PTGES (0.41) | PTGESPRSS12NPC1CYP2D6CYP2C9 | |
| SCHEMBL4847730 | 0.86 | PTGES (0.45) | PTGESHDAC1HDAC2PRSS12NPC1 | |
| SCHEMBL4785770 | 0.85 | PTGES (0.42) | PTGESPRSS12NPC1CYP2D6CYP2C9 | |
| SCHEMBL4804034 | 0.83 | PTGES (0.40) | PTGESHDAC8PRSS12CYP2D6CYP2C9 | |
| SCHEMBL4785631 | 0.81 | PTGES (0.41) | PTGESPRSS12CYP2D6CYP2C9 | |
| SCHEMBL4786443 | 0.79 | PTGES (0.44) | PTGESHDAC1PRSS12 | |
| SCHEMBL4786495 | 0.77 | PTGES (0.47) | PTGESHDAC3HDAC1HDAC2PRSS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008084218-A1 | BENZAZOLE DERIVATIVES FOR THE TREATMENT OF INFLAMMATIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-17 | — | — | WO | disclosed |