Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 11/20 | 0.40 |
| ▸ | PRSS12 | P56730 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4785770 | 0.96 | PTGES (0.42) | PTGESPRSS12MAPTALDH1A1LMNA | |
| SCHEMBL4785631 | 0.93 | PTGES (0.41) | PTGESPRSS12MAPTALDH1A1LMNA | |
| SCHEMBL4786434 | 0.88 | PTGES (0.44) | PTGESPRSS12MAPTALDH1A1LMNA | |
| SCHEMBL4847730 | 0.85 | PTGES (0.45) | PTGESPRSS12MAPTALDH1A1LMNA | |
| SCHEMBL4785781 | 0.83 | PTGES (0.41) | PTGESPRSS12MAPTALDH1A1LMNA | |
| SCHEMBL4786085 | 0.83 | PTGES (0.41) | PTGESPRSS12CYP2D6CYP2C9HDAC8 | |
| SCHEMBL4787275 | 0.83 | PTGES (0.41) | PTGESPRSS12MAPTALDH1A1LMNA | |
| SCHEMBL4786443 | 0.79 | PTGES (0.44) | PTGESPRSS12MAPTALDH1A1LMNA | |
| SCHEMBL4786495 | 0.77 | PTGES (0.47) | PTGESPRSS12 | |
| SCHEMBL4784998 | 0.76 | PTGES (0.45) | PTGESPRSS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008084218-A1 | BENZAZOLE DERIVATIVES FOR THE TREATMENT OF INFLAMMATIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-17 | — | — | WO | disclosed |