Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089820 | 0.90 | MAPT (0.47) | MAPTKMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL8089825 | 0.90 | MAPT (0.65) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL6031714 | 0.89 | ALDH1A1 (0.59) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8090310 | 0.85 | POLB (0.51) | MAPTALDH1A1KMT2AMEN1POLB | |
| SCHEMBL8098928 | 0.85 | MAPT (0.44) | MAPTKMT2AMEN1 | |
| SCHEMBL11026073 | 0.84 | MAPT (0.43) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8089677 | 0.81 | MAPT (0.64) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8103262 | 0.79 | MAPT (0.62) | MAPTALDH1A1KMT2AMEN1GAA | |
| SCHEMBL8099209 | 0.77 | MAPT (0.55) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8082058 | 0.77 | MAPT (0.59) | MAPTKMT2AMEN1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | disclosed |