Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.48 |
| ▸ | CTSG | P08311 | 2/20 | 0.46 |
| ▸ | CMA1 | P23946 | 2/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8082058 | 0.85 | MAPT (0.59) | MAPTKMT2AMEN1SLC6A2SLC6A4 | |
| SCHEMBL8098719 | 0.85 | MAPT (0.59) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL8099209 | 0.85 | MAPT (0.55) | MAPTKMT2AMEN1SLC6A2SLC6A4 | |
| SCHEMBL5154445 | 0.83 | SLC6A2 (0.52) | MAPTKMT2AMEN1SLC6A2SLC6A4 | |
| SCHEMBL8090617 | 0.82 | MAPT (0.58) | MAPTKMT2AMEN1SLC6A2SLC6A4 | |
| SCHEMBL8103751 | 0.82 | MAPT (0.55) | MAPT | |
| SCHEMBL4786129 | 0.81 | MAPT (0.55) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL8089825 | 0.80 | MAPT (0.65) | MAPTKMT2AMEN1CTSGCMA1 | |
| SCHEMBL8096492 | 0.79 | MAPT (0.64) | MAPTKMT2AMEN1SLC6A4CTSG | |
| SCHEMBL8103262 | 0.78 | MAPT (0.62) | MAPTKMT2AMEN1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |
| US-4664694-A | NONPHYTOTOXIC | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1987-05-12 | — | — | US | disclosed |
| EP-0200415-A1 | Substituted thiazolidinones | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1986-11-05 | — | — | EP | disclosed |