Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090617 | 0.85 | MAPT (0.58) | MAPTKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL8089825 | 0.82 | MAPT (0.65) | MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL4786129 | 0.79 | MAPT (0.55) | MAPTTSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL8089677 | 0.78 | MAPT (0.64) | MAPTKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL8098719 | 0.78 | MAPT (0.59) | MAPTDRD2DRD3KMT2AMEN1 | |
| SCHEMBL8097250 | 0.77 | MAPT (1.00) | MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL8299106 | 0.75 | KMT2A (0.55) | MAPTTSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL8082058 | 0.74 | MAPT (0.59) | MAPTKMT2AMEN1 | |
| SCHEMBL8103751 | 0.71 | MAPT (0.55) | MAPT | |
| SCHEMBL8089820 | 0.71 | MAPT (0.47) | MAPTTSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |
| US-4664694-A | NONPHYTOTOXIC | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1987-05-12 | — | — | US | disclosed |
| EP-0200415-A1 | Substituted thiazolidinones | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1986-11-05 | — | — | EP | disclosed |