Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786129 | 0.85 | MAPT (0.55) | POLBGAAALDH1A1MAPK1RAB9A | |
| SCHEMBL8099334 | 0.82 | MGLL (0.49) | MGLLMAPT | |
| SCHEMBL8089820 | 0.80 | MAPT (0.47) | POLBMAPK1RAB9ANPC1PKM | |
| SCHEMBL8592552 | 0.79 | MAPT (0.46) | POLBL3MBTL1KMT2AMAPTMEN1 | |
| SCHEMBL29749933 | 0.77 | MAPT (0.47) | POLBGAAALDH1A1MAPK1RAB9A | |
| SCHEMBL8089825 | 0.77 | MAPT (0.65) | ALDH1A1MGLLKMT2AMAPTMEN1 | |
| SCHEMBL8098867 | 0.76 | MAPT (0.40) | GAAALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL6031714 | 0.76 | ALDH1A1 (0.59) | POLBGAAALDH1A1RAB9ANPC1 | |
| SCHEMBL2046118 | 0.73 | POLB (0.61) | POLBGAARAB9ANPC1PKM | |
| SCHEMBL23643027 | 0.72 | POLB (0.47) | POLBGAARAB9ANPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114634502-B | 3-Aryl substituted thiazolidine-4-ketone-2-methylene hydrazono methylene-1H-indole derivative and preparation method thereof | 复旦大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-114634506-B | Substituted 1H-indol-2-one-yl-3, 5-substituted aryl-1, 3-thiazolidinedione derivatives | 复旦大学 | 2024-04-19 | — | — | CN | disclosed |
| CN-114634502-A | 3-aryl substituted thiazolidine-4-ketone-2-ylidenehydrazonomethylene-1H-indole derivatives and preparation method thereof | 复旦大学 | 2022-06-17 | — | — | CN | disclosed |
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |