Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | CES2 | O00748 | 1/20 | 0.59 |
| ▸ | CES1 | P23141 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL194888 | 0.83 | RAB9A (0.83) | RAB9ACES2CES1ALDH1A1MAPT | |
| SCHEMBL303244 | 0.79 | ALDH1A1 (0.61) | RAB9AALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL8695963 | 0.78 | RAB9A (0.63) | RAB9AALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL9187568 | 0.77 | RAB9A (0.67) | RAB9ACES2CES1ALDH1A1MAPT | |
| SCHEMBL4174554 | 0.77 | RAB9A (0.73) | RAB9AALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL11129136 | 0.77 | RAB9A (0.66) | RAB9ACES2CES1ALDH1A1MAPT | |
| Butane SCHEMBL11690769 | 0.76 | MAPT (0.57) | RAB9AALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL2124043 | 0.76 | RAB9A (0.55) | RAB9AALDH1A1MAPTHPGDNPC1 | |
| SCHEMBL4140401 | 0.75 | RAB9A (1.00) | RAB9ACES2CES1ALDH1A1MAPT | |
| SCHEMBL4785681 | 0.75 | CES2 (0.63) | CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008077646-A1 | NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-07-03 | — | — | WO | disclosed |