Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 12/20 | 0.49 |
| ▸ | PDE4A | P27815 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 11/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 4/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733110 | 0.91 | ITGA4 (0.59) | ITGA4PDE4AKCNH2ITGB1ITGB7 | |
| SCHEMBL12889776 | 0.78 | ITGA4 (0.48) | ITGA4ITGB1ITGB7ITGA2 | |
| SCHEMBL7428016 | 0.74 | ITGA4 (0.58) | ITGA4ITGB1ITGB7ITGB3ITGAV | |
| Hydrochloric Acid SCHEMBL6510331 | 0.73 | ITGA4 (0.57) | ITGA4ITGB1ITGB7ITGB3ITGAV | |
| SCHEMBL4786565 | 0.73 | ITGA4 (0.58) | ITGA4ITGB1 | |
| SCHEMBL4730881 | 0.72 | ITGA4 (0.53) | ITGA4ITGB1ITGB7 | |
| SCHEMBL13819259 | 0.69 | ITGA4 (0.54) | ITGA4ITGB1ITGB7 | |
| SCHEMBL4783431 | 0.69 | ITGA4 (0.59) | ITGA4ITGB1ITGB7ITGB3ITGAV | |
| SCHEMBL4734982 | 0.69 | ITGA4 (0.49) | ITGA4ITGB1ITGB7ITGB3ITGAV | |
| SCHEMBL4735439 | 0.69 | ITGA4 (0.65) | ITGA4ITGB1ITGB7ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008064823-A1 | BICYCLIC AND HETEROBICYCLIC DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB PHARMA, S.A. (BE) | 2008-06-05 | — | — | WO | claimed |
| WO-2008064823-A1 | BICYCLIC AND HETEROBICYCLIC DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB PHARMA, S.A. (BE) | 2008-06-05 | — | — | WO | disclosed |