Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2634894 | 0.78 | CA12 (0.61) | CA12ALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL4661669 | 0.76 | CA12 (0.66) | CA12ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL6050985 | 0.75 | LMNA (0.64) | L3MBTL1KDM4EMEN1KMT2AKDM1A | |
| SCHEMBL26116967 | 0.74 | MEN1 (0.49) | ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL1115783 | 0.73 | CA2 (0.55) | CA12MEN1KMT2AACHE | |
| SCHEMBL11779612 | 0.72 | ALDH1A1 (0.87) | ALDH1A1L3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL17272408 | 0.71 | CA12 (0.53) | CA12ALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL4973666 | 0.71 | CYP19A1 (0.59) | ALDH1A1KDM4EMEN1KMT2AKDM1A | |
| SCHEMBL2060922 | 0.71 | ALDH1A1 (0.58) | CA12ALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL3811125 | 0.71 | CA12 (0.59) | CA12ALDH1A1L3MBTL1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896744-B | Selective EGFR inhibitor | 成都先导药物开发股份有限公司 | 2024-04-16 | — | — | CN | disclosed |
| EP-1991532-A2 | COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY | Rigel Pharmaceuticals, Inc. (US) | 2008-11-19 | — | — | EP | disclosed |
| WO-2008118822-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY | RIGEL PHARMACEUTICALS, INC. (US) | 2008-10-02 | — | — | WO | disclosed |
| WO-2007098507-A2 | COMPOSITIONS AND METHODS FOR INHIBITION OF THE JAK PATHWAY | RIGEL PHARMACEUTICALS, INC. (US) | 2007-08-30 | — | — | WO | disclosed |