Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.53 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29540801 | 0.81 | KEAP1 (0.70) | CA12ALDH1A1MEN1KMT2APKM | |
| SCHEMBL22234206 | 0.81 | CYP19A1 (0.68) | CA12ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2634894 | 0.81 | CA12 (0.61) | CA12ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4786633 | 0.76 | CA12 (0.56) | CA12ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL4068758 | 0.76 | HTT (0.58) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL4661775 | 0.75 | CA2 (0.76) | CA12ALDH1A1VCAM1MAPTMEN1 | |
| SCHEMBL29258301 | 0.75 | CYP19A1 (0.59) | CA12ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL29258367 | 0.75 | CYP19A1 (0.59) | CA12ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5429675 | 0.75 | LMNA (0.57) | CA12ALDH1A1VCAM1MAPTLMNA | |
| SCHEMBL27639297 | 0.75 | CYP19A1 (0.56) | CA12ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007760-A1 | NOVEL SUBSTITUTED-1, 1-DIOXO-BENZO[1,2,4]THIADIZIN-3-ONES, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007108569-A1 | NOVEL SUBSTITUTED-1, 1-DIOXO-BENZO[1,2,4]THIADIZIN-3-ONES, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KOREA RESERACH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2007-09-27 | — | — | WO | disclosed |