Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.65 |
| ▸ | LTA4H | P09960 | 2/20 | 0.55 |
| ▸ | MET | P08581 | 3/20 | 0.55 |
| ▸ | ESR1 | P03372 | 4/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.54 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7748549 | 0.83 | ESR1 (0.66) | LTA4HESR1ESR2KCNH2 | |
| SCHEMBL4967552 | 0.80 | KDR (0.59) | KDRMETESR1ESR2MCHR1 | |
| SCHEMBL3092657 | 0.79 | ESR1 (0.65) | ESR1ESR2KCNH2 | |
| SCHEMBL7738182 | 0.78 | ESR1 (0.64) | LTA4HESR1ESR2KCNH2 | |
| SCHEMBL8593768 | 0.76 | ESR1 (0.67) | ESR1ESR2KCNH2 | |
| SCHEMBL8708988 | 0.76 | ESR1 (0.67) | ESR1ESR2KCNH2 | |
| SCHEMBL14970484 | 0.75 | LTA4H (0.97) | LTA4HKCNH2HRH4HRH3 | |
| SCHEMBL4968829 | 0.75 | GCGR (0.69) | KDRMCHR1EPHX2KCNH2HRH3 | |
| Hydrochloric Acid SCHEMBL1319661 | 0.74 | BACE1 (0.52) | KDRLTA4HMETKCNH2HRH4 | |
| SCHEMBL1899201 | 0.74 | LTA4H (1.00) | LTA4HKCNH2HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130571-A1 | NUCLEAR RECEPTOR BINDING AGENTS | GTX, INC. (US) | 2008-10-30 | — | — | WO | disclosed |