Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 14/20 | 0.43 |
| ▸ | CNR2 | P34972 | 12/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4789197 | 0.88 | CNR1 (0.43) | CNR1CNR2 | |
| SCHEMBL4788342 | 0.86 | CRHR1 (0.46) | CNR1CNR2 | |
| SCHEMBL14020262 | 0.84 | MAPT (0.41) | CNR1CNR2CYP2C9CYP2C19KMT2A | |
| SCHEMBL4751343 | 0.81 | TDP2 (0.41) | CNR1CNR2CYP2C9CYP2C19KMT2A | |
| SCHEMBL4788229 | 0.81 | MAPT (0.39) | CNR1CNR2CYP2C9CYP2C19KMT2A | |
| SCHEMBL4787160 | 0.81 | MAPT (0.45) | CNR1CNR2KMT2A | |
| SCHEMBL4787973 | 0.79 | CNR1 (0.47) | CNR1CNR2 | |
| SCHEMBL14020279 | 0.78 | MAPT (0.43) | CNR1CNR2KMT2A | |
| SCHEMBL4788000 | 0.75 | LMNA (0.40) | MEN1KMT2A | |
| SCHEMBL4789117 | 0.74 | TP53 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008134300-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-11-06 | — | — | WO | claimed |
| WO-2008134300-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-11-06 | — | — | WO | disclosed |
| WO-2008134300-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-11-06 | — | — | WO | disclosed |