Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 8/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786913 | 1.00 | CCKBR (0.42) | CCKBRSLC6A4HTR6MAPTNPC1 | |
| SCHEMBL4788912 | 0.80 | HRH3 (0.44) | CCKBRSLC6A4HTR6MAPTNPC1 | |
| SCHEMBL4788914 | 0.80 | HRH3 (0.44) | CCKBRSLC6A4HTR6MAPTNPC1 | |
| SCHEMBL14498457 | 0.72 | CCKBR (0.45) | CCKBRSLC6A4HTR6 | |
| SCHEMBL11401359 | 0.66 | SLC6A4 (0.59) | SLC6A4HTR6MAPTPOLBCYP3A4 | |
| SCHEMBL3132122 | 0.66 | IMPDH2 (0.53) | MAPTSMN1; SMN2CYP3A4MEN1KMT2A | |
| SCHEMBL12765737 | 0.64 | SLC6A4 (0.81) | SLC6A4HTR6MAPTPOLBCYP3A4 | |
| SCHEMBL3383624 | 0.63 | CCKBR (0.56) | CCKBRSLC6A4MAPTPOLBKMT2A | |
| SCHEMBL22012837 | 0.62 | KMT2A (0.60) | SLC6A4HTR6MAPTPOLBCYP3A4 | |
| SCHEMBL8568165 | 0.61 | HTR1D (0.55) | SLC6A4HTR6MAPTPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008129129-A1 | HETEROCYCLIC PHENYL CARBAMATES AS NOVEL FAAH-INHIBITORS | KUOPION YLIOPISTO (FI) | 2008-10-30 | — | — | WO | disclosed |