Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.81 |
| ▸ | HTR6 | P50406 | 8/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | AHR | P35869 | 1/20 | 0.62 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL733304 | 0.91 | SLC6A4 (0.73) | SLC6A4HTR6KMT2AMAPTMEN1 | |
| SCHEMBL1998835 | 0.90 | SLC6A4 (1.00) | SLC6A4HTR6KMT2AMAPTMEN1 | |
| SCHEMBL30592374 | 0.90 | SLC6A4 (1.00) | SLC6A4HTR6KMT2AMAPTMEN1 | |
| SCHEMBL4822564 | 0.85 | SLC6A4 (0.71) | SLC6A4HTR6KMT2AMAPTMEN1 | |
| SCHEMBL27923059 | 0.83 | SLC6A4 (0.82) | SLC6A4HTR6KMT2AMAPTMEN1 | |
| SCHEMBL14282331 | 0.83 | HTR1A (0.65) | SLC6A4HTR6BCHECYP2D6 | |
| SCHEMBL24178316 | 0.81 | HTR6 (0.69) | SLC6A4HTR6KMT2AMAPTMEN1 | |
| SCHEMBL30361714 | 0.81 | HTR6 (0.69) | SLC6A4HTR6KMT2AMAPTMEN1 | |
| SCHEMBL24178288 | 0.81 | HTR6 (0.69) | SLC6A4HTR6KMT2AMAPTMEN1 | |
| SCHEMBL31302667 | 0.81 | SLC6A4 (0.68) | SLC6A4HTR6KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873305-B2 | Processes for synthesis of substituted indole intermediates for the synthesis of serd compounds | GENENTECH, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| CN-108101830-B | A kind of 3- replaces the preparation method of Oxoindole and derivative | 中国科学院成都生物研究所 | 2019-08-23 | — | — | CN | disclosed |
| US-7897619-B2 | Heterocyclic modulators of PKB | AMGEN INC. (US) | 2011-03-01 | — | — | US | disclosed |
| US-20090275592-A1 | Heterocyclic modulators of PKB | AMGEN INC. (US) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11873305-B2 | Processes for synthesis of substituted indole intermediates for the synthesis of serd compounds | WEE1, WEE2, INMT | SLC6A4 626/4885HTR6 425/4885KMT2A 2114/4885 |
| US-20090275592-A1 | Heterocyclic modulators of PKB | MTOR, PDK1, EIF4EBP1 | SLC6A4 4618/4885HTR6 1758/4885KMT2A 3140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.