Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | HTR1A | P08908 | 1/20 | 0.62 |
| ▸ | HTR1D | P28221 | 1/20 | 0.62 |
| ▸ | HTR1B | P28222 | 1/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786990 | 1.00 | HTR6 (0.62) | HTR6ALDH1A1LMNAKDM4ETP53 | |
| SCHEMBL14045634 | 0.94 | CYP3A4 (0.62) | HTR6ALDH1A1LMNAKDM4ETP53 | |
| SCHEMBL4788896 | 0.87 | CYP3A4 (0.68) | HTR6ALDH1A1LMNAKDM4ETP53 | |
| SCHEMBL4788892 | 0.87 | CYP3A4 (0.68) | HTR6ALDH1A1LMNAKDM4ETP53 | |
| SCHEMBL2975416 | 0.78 | HTR6 (1.00) | HTR6HTR1AHTR1DHTR1BMTNR1A | |
| SCHEMBL30058389 | 0.77 | HTR1D (1.00) | HTR6ALDH1A1LMNAKDM4ETP53 | |
| SCHEMBL4784832 | 0.77 | HTR1D (1.00) | HTR6ALDH1A1LMNAKDM4ETP53 | |
| SCHEMBL4784837 | 0.77 | HTR1D (1.00) | HTR6ALDH1A1LMNAKDM4ETP53 | |
| SCHEMBL28891808 | 0.74 | THRB (0.73) | ALDH1A1LMNACYP1A2CYP3A4HDAC6 | |
| SCHEMBL4785841 | 0.72 | CYP3A4 (0.90) | HTR6ALDH1A1LMNAKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008118445-A9 | METHODS TO QUENCH LIGHT FROM OPTICAL REACTIONS | PROMEGA CORP (US) | 2008-12-04 | — | — | WO | claimed |
| US-20080248511-A1 | METHODS TO QUENCH LIGHT FROM OPTICAL REACTIONS | PROMEGA CORPORATION | 2008-10-09 | — | — | US | claimed |
| WO-2008118445-A1 | METHODS TO QUENCH LIGHT FROM OPTICAL REACTIONS | PROMEGA CORPORATION (US) | 2008-10-02 | — | — | WO | claimed |
| WO-2008118445-A9 | METHODS TO QUENCH LIGHT FROM OPTICAL REACTIONS | PROMEGA CORP (US) | 2008-12-04 | — | — | WO | disclosed |
| US-20080248511-A1 | METHODS TO QUENCH LIGHT FROM OPTICAL REACTIONS | PROMEGA CORPORATION | 2008-10-09 | — | — | US | disclosed |
| WO-2008118445-A1 | METHODS TO QUENCH LIGHT FROM OPTICAL REACTIONS | PROMEGA CORPORATION (US) | 2008-10-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080248511-A1 | METHODS TO QUENCH LIGHT FROM OPTICAL REACTIONS | GLO1, ESD, GLB1 | HTR6 1625/4885ALDH1A1 349/4885LMNA 2711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.