Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743532 | 0.77 | GFER (0.70) | ALDH1A1HTTNPSR1GFERCA1 | |
| SCHEMBL747924 | 0.76 | KMT2A (0.53) | ALDH1A1HTTNPSR1MAPTKMT2A | |
| SCHEMBL4743542 | 0.74 | ALDH1A1 (0.52) | ALDH1A1HTTNPSR1GFERKCNA5 | |
| SCHEMBL748256 | 0.74 | HCRTR1 (0.55) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL4743949 | 0.72 | ALDH1A1 (0.64) | ALDH1A1HTTNPSR1GFERMAPT | |
| SCHEMBL4745876 | 0.71 | CA1 (0.61) | ALDH1A1HTTNPSR1GFERMAPT | |
| SCHEMBL4746811 | 0.71 | MAPT (0.59) | ALDH1A1HTTNPSR1GFERMAPT | |
| SCHEMBL4746660 | 0.71 | ALDH1A1 (0.59) | ALDH1A1HTTNPSR1GFERMAPT | |
| SCHEMBL4743525 | 0.70 | CA1 (0.56) | ALDH1A1HTTNPSR1GFERMAPT | |
| SCHEMBL4747930 | 0.70 | MAPT (0.55) | ALDH1A1HTTNPSR1GFERMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | claimed |
| WO-2008112674-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2008-09-18 | — | — | WO | disclosed |