Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743057 | 0.91 | ALDH1A1 (0.47) | TSHRPOLBKMT2ALMNAALDH1A1 | |
| SCHEMBL4745419 | 0.85 | MCOLN3 (0.46) | TSHRKMT2ALMNAALDH1A1 | |
| SCHEMBL5291346 | 0.84 | ALDH1A1 (0.51) | POLBKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4805415 | 0.84 | KMT2A (0.49) | POLBKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4745387 | 0.84 | TSHR (0.51) | TSHRGFERPOLBKMT2ALMNA | |
| SCHEMBL4786482 | 0.82 | TSHR (0.42) | TSHRGFERPOLBKMT2ARXFP1 | |
| SCHEMBL4746895 | 0.82 | MAPT (0.49) | POLBKMT2ALMNAALDH1A1 | |
| SCHEMBL4788023 | 0.81 | TSHR (0.43) | TSHRGFERPOLBKMT2ARXFP1 | |
| SCHEMBL4784036 | 0.81 | TSHR (0.67) | TSHRGFERPOLBRXFP1LMNA | |
| SCHEMBL4787284 | 0.80 | TSHR (0.52) | TSHRGFERPOLBKMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115259-A2 | DERIVATIVES OF BENZOXADIAZOLE SUITABLE FOR THE TREATMENT OF CELL PROLIFERATIVE DISEASES | RIGEL PHARMACEUTICALS, INC. (US) | 2008-09-25 | — | — | WO | claimed |