Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.75 |
| ▸ | HTR1A | P08908 | 2/20 | 0.75 |
| ▸ | HTR1D | P28221 | 2/20 | 0.75 |
| ▸ | HTR1B | P28222 | 2/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.75 |
| ▸ | TP53 | P04637 | 1/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.75 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.75 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4787406 | 1.00 | ALDH1A1 (0.75) | ALDH1A1HTR1AHTR1DHTR1BKDM4E | |
| SCHEMBL18622645 | 0.88 | HTR1A (0.81) | ALDH1A1HTR1AHTR1DHTR1BKDM4E | |
| SCHEMBL4784967 | 0.87 | HTR1A (0.80) | ALDH1A1HTR1AHTR1DHTR1BKDM4E | |
| SCHEMBL4788190 | 0.87 | HTR1A (0.80) | ALDH1A1HTR1AHTR1DHTR1BKDM4E | |
| SCHEMBL4784970 | 0.87 | HTR1A (0.80) | ALDH1A1HTR1AHTR1DHTR1BKDM4E | |
| SCHEMBL30058389 | 0.86 | HTR1D (1.00) | ALDH1A1HTR1AHTR1DHTR1BKDM4E | |
| SCHEMBL4784832 | 0.86 | HTR1D (1.00) | ALDH1A1HTR1AHTR1DHTR1BKDM4E | |
| SCHEMBL4784837 | 0.86 | HTR1D (1.00) | ALDH1A1HTR1AHTR1DHTR1BKDM4E | |
| SCHEMBL10531771 | 0.83 | HTR1D (0.77) | ALDH1A1HTR1AHTR1DHTR1BKDM4E | |
| SCHEMBL10531774 | 0.82 | HTR1B (0.72) | ALDH1A1HTR1AHTR1DHTR1BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008118445-A9 | METHODS TO QUENCH LIGHT FROM OPTICAL REACTIONS | PROMEGA CORP (US) | 2008-12-04 | — | — | WO | claimed |
| US-20080248511-A1 | METHODS TO QUENCH LIGHT FROM OPTICAL REACTIONS | PROMEGA CORPORATION | 2008-10-09 | — | — | US | claimed |
| WO-2008118445-A1 | METHODS TO QUENCH LIGHT FROM OPTICAL REACTIONS | PROMEGA CORPORATION (US) | 2008-10-02 | — | — | WO | claimed |
| WO-2008118445-A9 | METHODS TO QUENCH LIGHT FROM OPTICAL REACTIONS | PROMEGA CORP (US) | 2008-12-04 | — | — | WO | disclosed |
| US-20080248511-A1 | METHODS TO QUENCH LIGHT FROM OPTICAL REACTIONS | PROMEGA CORPORATION | 2008-10-09 | — | — | US | disclosed |
| US-20080248511-A1 | METHODS TO QUENCH LIGHT FROM OPTICAL REACTIONS | PROMEGA CORPORATION | 2008-10-09 | — | — | US | disclosed |
| WO-2008118445-A1 | METHODS TO QUENCH LIGHT FROM OPTICAL REACTIONS | PROMEGA CORPORATION (US) | 2008-10-02 | — | — | WO | disclosed |
| US-4870096-A | MIGRAINE | GLAXO GROUP LIMITED (GB) | 1989-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080248511-A1 | METHODS TO QUENCH LIGHT FROM OPTICAL REACTIONS | GLO1, ESD, GLB1 | ALDH1A1 349/4885HTR1A 2628/4885HTR1D 3214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.