Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PTPRB | P23467 | 1/20 | 0.38 |
| ▸ | OGG1 | O15527 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20428035 | 0.76 | HPGD (0.50) | ALDH1A1LMNAL3MBTL1HPGDRECQL | |
| SCHEMBL4098513 | 0.76 | NPC1 (0.52) | ALDH1A1LMNAHPGDKDM4ERECQL | |
| SCHEMBL14022449 | 0.74 | NPC1 (0.47) | ALDH1A1LMNAL3MBTL1HPGDKDM4E | |
| SCHEMBL21100162 | 0.72 | ALDH1A1 (0.50) | ALDH1A1LMNAHPGDKDM4EGAA | |
| SCHEMBL1927578 | 0.71 | TDP1 (0.60) | ALDH1A1HPGDKDM4EGAAMAPT | |
| SCHEMBL1928099 | 0.71 | LMNA (0.45) | ALDH1A1LMNAL3MBTL1HPGDKDM4E | |
| SCHEMBL28992828 | 0.70 | MAPT (0.43) | ALDH1A1HPGDKDM4ERECQLGAA | |
| SCHEMBL772894 | 0.69 | KMT2A (0.56) | ALDH1A1HPGDKDM4EMAPTMEN1 | |
| SCHEMBL26089966 | 0.68 | MEN1 (0.42) | ALDH1A1LMNAHPGDKDM4ERECQL | |
| SCHEMBL12370955 | 0.67 | ALOX15 (0.61) | LMNAHPGDMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135824-A1 | OXYALKYLPYRAZOLE COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2008-11-13 | — | — | WO | disclosed |
| WO-2008135824-A1 | OXYALKYLPYRAZOLE COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2008-11-13 | — | — | WO | disclosed |