Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.63 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.58 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | RAF1 | P04049 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788021 | 0.99 | EPHX2 (0.64) | EPHX2CHRNA7KCNH2MCHR1GAA | |
| SCHEMBL4787642 | 0.96 | EPHX2 (0.63) | EPHX2CHRNA7KCNH2MCHR1GAA | |
| SCHEMBL4786204 | 0.93 | EPHX2 (0.60) | EPHX2CHRNA7KCNH2MCHR1MCHR2 | |
| SCHEMBL4786227 | 0.90 | EPHX2 (0.59) | EPHX2CHRNA7KCNH2MCHR1MCHR2 | |
| SCHEMBL4786966 | 0.90 | EPHX2 (0.59) | EPHX2CHRNA7KCNH2MCHR1MCHR2 | |
| SCHEMBL4786193 | 0.90 | EPHX2 (0.56) | EPHX2MCHR1RAB9AMCHR2MAPT | |
| SCHEMBL4788049 | 0.89 | EPHX2 (0.69) | EPHX2RAB9AMAPTMEN1KMT2A | |
| SCHEMBL4786207 | 0.87 | EPHX2 (0.61) | EPHX2CHRNA7KCNH2MAPTNAMPT | |
| SCHEMBL4788178 | 0.87 | EPHX2 (0.58) | EPHX2CHRNA7KCNH2MCHR1MCHR2 | |
| SCHEMBL14041773 | 0.85 | EPHX2 (0.59) | EPHX2RAB9APOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008122667-A2 | UREYLENE DERIVATIVES | SCHOOL OF PHARMACY (GB) | 2008-10-16 | — | — | WO | disclosed |