Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.63 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.54 |
| ▸ | HTR3A | P46098 | 3/20 | 0.52 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788021 | 0.97 | EPHX2 (0.64) | EPHX2CHRNA7KCNH2HPSEHTT | |
| SCHEMBL4787450 | 0.96 | EPHX2 (0.63) | EPHX2CHRNA7KCNH2HTTGAA | |
| SCHEMBL4786966 | 0.94 | EPHX2 (0.59) | EPHX2CHRNA7KCNH2HTR3AALDH1A1 | |
| SCHEMBL4788178 | 0.91 | EPHX2 (0.58) | EPHX2CHRNA7KCNH2HTR3AHPSE | |
| SCHEMBL4786204 | 0.91 | EPHX2 (0.60) | EPHX2CHRNA7KCNH2MCHR1 | |
| SCHEMBL4788314 | 0.88 | EPHX2 (0.60) | EPHX2CHRNA7KCNH2HTR3A | |
| SCHEMBL4786227 | 0.88 | EPHX2 (0.59) | EPHX2CHRNA7KCNH2HPSEMCHR1 | |
| SCHEMBL4786193 | 0.87 | EPHX2 (0.56) | EPHX2HTR3ARAB9ATP53MCHR1 | |
| SCHEMBL4788049 | 0.87 | EPHX2 (0.69) | EPHX2RAB9AALDH1A1TP53KDR | |
| SCHEMBL4788497 | 0.87 | HTR3A (0.55) | EPHX2CHRNA7KCNH2HTR3ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008122667-A2 | UREYLENE DERIVATIVES | SCHOOL OF PHARMACY (GB) | 2008-10-16 | — | — | WO | disclosed |