Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 15/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788021 | 0.90 | EPHX2 (0.64) | EPHX2MAPTALDH1A1TP53RAB9A | |
| SCHEMBL4787450 | 0.89 | EPHX2 (0.63) | EPHX2MEN1MAPTKMT2ARAB9A | |
| SCHEMBL4787642 | 0.87 | EPHX2 (0.63) | EPHX2ALDH1A1TP53RAB9AKDR | |
| SCHEMBL14041745 | 0.86 | EPHX2 (0.69) | EPHX2LMNAKMT2ANPC1ALDH1A1 | |
| SCHEMBL4786204 | 0.84 | EPHX2 (0.60) | EPHX2MAPT | |
| SCHEMBL4786227 | 0.81 | EPHX2 (0.59) | EPHX2MAPT | |
| SCHEMBL4786966 | 0.81 | EPHX2 (0.59) | EPHX2MAPTALDH1A1 | |
| SCHEMBL4786193 | 0.81 | EPHX2 (0.56) | EPHX2MEN1MAPTKMT2ANPC1 | |
| SCHEMBL4788178 | 0.78 | EPHX2 (0.58) | EPHX2 | |
| SCHEMBL4786207 | 0.78 | EPHX2 (0.61) | EPHX2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008122667-A2 | UREYLENE DERIVATIVES | SCHOOL OF PHARMACY (GB) | 2008-10-16 | — | — | WO | disclosed |