Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 2/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28940803 | 0.87 | CA2 (0.45) | CA2CA1CA9CA5AGAA | |
| SCHEMBL4700846 | 0.85 | CA1 (0.45) | CA2CA1CA9CA5AGAA | |
| SCHEMBL28519039 | 0.81 | L3MBTL1 (0.42) | GAAALDH1A1KDM4EMAPTCASP7 | |
| SCHEMBL27530848 | 0.81 | KDM4E (0.56) | GAAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL2920746 | 0.81 | PTGER4 (0.56) | CA2CA1CA9CA5AGAA | |
| SCHEMBL4268094 | 0.81 | KDM4E (0.44) | CA2CA1CA9CA5AALDH1A1 | |
| SCHEMBL1357981 | 0.79 | CA1 (0.42) | CA2CA1CA9CA5AGAA | |
| SCHEMBL1355241 | 0.78 | KDM4E (0.49) | CA2CA1CA9CA5AGAA | |
| SCHEMBL5548265 | 0.77 | CA1 (0.41) | CA2CA1CA9CA5AALDH1A1 | |
| SCHEMBL4703972 | 0.77 | CDK1 (0.40) | CA2CA1CA9CA5AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008119773-A1 | AMIDE DERIVATIVES AS INHIBITORS OF ASPARTYL PROTEASES | MEDIVIR AB (SE) | 2008-10-09 | — | — | WO | disclosed |